ORGANIC CHEMISTRY
L T P
3 - 2
RATIONALE
Diploma holders in Medical
Laboratory Technology are supposed to know about the chemical properties of
various materials. For this purpose, it is essential that they should be
equipped with knowledge and skill covering topics like solutions, acids, bases
and salts, electrolytes, ionization, organic chemistry such as hydrocarbons,
alcohols, ethers, carbohydrates, lipids, proteins and enzymes etc., so as to
enable them to perform various activities in a medical laboratory effectively.
DETAILED CONTENTS
1.
Introduction to organic
chemistry (2 hrs)
1.1 Importance of organic
compounds
1.2 Comparison of organic and Inorganic compounds
1.3 Properties of Carbon
2. IUPAC Nomenclature of Organic Compounds
(4 hrs)
2.1
Hydrocarbons
2.2
Alcohols and Ethers
2.3
Aldehydes and Ketones
2.4
Carboxylic
Acids
3. Hydro carbons
(6
hrs)
3.1 Saturated hydrocarbons
3.2 Unsaturated hydrocarbons
3.3 Sources of hydrocarbons
3.4 Halogen derivatives of hydrocarbons
4. Alcohols and ethers
(5
hrs)
General
introduction, classification, preparation and properties of
4.1 Methyl alcohol, Ethyl alcohol and
glycerol
4.2 Diethyl ether
5. Aldehydes and Ketones
(5
hrs)
General
introduction, classification, preparation and properties of
5.1 Methanal and ethanal
5.2 Propanone
6. Carboxylic
Acids
General
Introduction, classification, preparation, properties and uses of
6.1
Methanoic acid
6.2
Ethanoic acid
6.3
Benzoic acid
7. Carbohydrates
Definition
optical activity, mutarotation, composition, sources, classification. Reactions of carbohydrates, important
monosaccharides, disaccharides, polysaccharides. Breakage of glucose, fructose, galactose, lactose, maltose. Role of carbohydrates.
8. Lipids
Definition,
classification, fatty acids, phospholipids, triglycerides, sterol, ergesterol,
cholestrol and reactions of fats. Role
of lipids.
9. Proteins
Definition,
classification, composition, molecular weight, hydrolysis, amino acids. Structure, colour reactions and properties
of proteins.
10. Enzymes
10.1
Definition
10.2
Classification
10.3
Chemical nature of enzymes
10.4
Properties of Enzymes
10.5
Factors affecting enzyme activity
10.6
Activation of Enzymes
10.7
Enzyme Inhibitors
10.8
Enzymes of Diagnostic Importance
LIST OF PRACTICALS
1.
lodometric titrations oxidation reduction titrations,
Acid-base titrations
2.
Sponification of fatty acids
3.
Distinction between aldehydes and ketones
4.
Detection of carbohydrates
5.
Detection of proteins
6.
Detection of lipids
RECOMMENDED BOOKS
1.
Modern’s Abc of Chemistry Vol I and II by Dr. S.P.Jauhar,
Modern Publishers, New Delhi
2.
A textbook of Biochemistry and Clinical Pathology by Sukhdev
Singh and Om Parkash
SUGGESTED DISTRIBUTION OF MARKS
|
Topic No.
|
Time allotted (Hrs)
|
Marks Allotted (%)
|
|
1
|
2
|
5
|
|
2
|
4
|
8
|
|
3
|
6
|
12
|
|
4
|
5
|
10
|
|
5
|
5
|
10
|
|
6
|
5
|
10
|
|
7
|
6
|
10
|
|
8
|
5
|
10
|
|
9
|
5
|
10
|
|
10
|
5
|
15
|
|
Total
|
48
|
100
|
|